Rosh Internal Medicine Boost Practice Exam

Which is the first-line treatment for pericarditis?

1. Antibiotics and steroids

2. Colchicine and NSAIDs

3. Beta-blockers and diuretics

4. Pain management alone

The correct answer is: Colchicine and NSAIDs

The first-line treatment for pericarditis is colchicine and NSAIDs. This combination is effective in reducing inflammation and alleviating pain associated with pericarditis. Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to manage pain and inflammation, making them a cornerstone of treatment. Colchicine has also been shown to be beneficial in preventing recurrences of pericarditis and reducing symptoms. It works by inhibiting the inflammatory process, which is central to the pathophysiology of pericarditis. The use of colchicine in conjunction with NSAIDs not only addresses acute symptoms but also helps decrease the likelihood of future episodes. While antibiotics and steroids may be considered in certain specific situations, they are not recommended as first-line treatments for uncomplicated pericarditis. Antibiotics are only indicated if there is a bacterial infection, and steroids carry a risk of adverse effects and are typically reserved for more severe cases or where NSAIDs and colchicine are ineffective. Beta-blockers and diuretics are not appropriate for treating pericarditis; they are primarily used for other cardiovascular conditions, such as heart failure or arrhythmias. Pain management alone may provide temporary relief, but it does not address the underlying inflammation that