For a patient with intermittent claudication due to peripheral vascular disease, which combination of treatments is most appropriate?

The most appropriate combination of treatments for a patient with intermittent claudication due to peripheral vascular disease is centered on a comprehensive approach that addresses both symptom management and risk factor modification.

The correct answer includes aspirin, cilostazol, rosuvastatin, smoking cessation, and structured exercise. Aspirin is an antiplatelet agent that can help prevent thrombotic events in patients with vascular disease. Cilostazol is specifically indicated for the treatment of intermittent claudication, as it improves walking distance and quality of life by enhancing blood flow. Rosuvastatin, a statin, plays a crucial role in managing dyslipidemia and offers cardiovascular protective effects, thereby reducing overall cardiovascular risks.

Smoking cessation is vital, as smoking is a significant risk factor for the progression of peripheral vascular disease, and cessation can lead to improved outcomes. Structured exercise programs are particularly beneficial, as they have been shown to improve symptoms of claudication and increase walking distances.

This comprehensive treatment plan not only targets the symptoms of intermittent claudication but also helps to modify the underlying risk factors associated with peripheral vascular disease, addressing both the patient's present concerns and preventing future complications. Other options may not provide the same breadth of benefit or may lack certain critical